Principle of Glucose Measurements
Week 5 - Saturday
August 18th, 2018
Discussion:
In near infrared region, human soft tissue and the body fluid have large penetrating ability for the light spectrum because of it transparent characteristics. Some factors such as measurement environment and individual differences are playing some important roles for the light concentration to detect based on the theory and NIR spectroscopy characteristics.
From the NIR spectroscopy analysis, the concentration of human blood glucose can be reviewed at a band range 750 ~ 2500nm and human tissue depth at range between 1 ~ 100um. Human body detection parts can be exposed to some of the very low of the near infrared light radiation, and the human tissue will be triggered by the light reflection, transmission and absorption.
August 18th, 2018
Near-infrared (NIR) Diffuse Spectroscopy
Objective: To study the wavelength that use in diagnose the human skin tissue parameter.Discussion:
In near infrared region, human soft tissue and the body fluid have large penetrating ability for the light spectrum because of it transparent characteristics. Some factors such as measurement environment and individual differences are playing some important roles for the light concentration to detect based on the theory and NIR spectroscopy characteristics.
From the NIR spectroscopy analysis, the concentration of human blood glucose can be reviewed at a band range 750 ~ 2500nm and human tissue depth at range between 1 ~ 100um. Human body detection parts can be exposed to some of the very low of the near infrared light radiation, and the human tissue will be triggered by the light reflection, transmission and absorption.
Figure 1 Schematic of light path in blood
The light brightness scattered from the tissue may different which is due the different glucose concentration in blood. As shown in figure above, the glucose concentration in blood affects the light path or scattering the light beam that travel through the blood vessel.
Conclusion:
Resulting from the analysis, the human blood glucose concentration can be achieved at normal band range between 950 - 2100nm, which can radiate into human skin tissue at depth between 1 - 100um. This cases are applied to the photoplethysmography or called PPG which the most used principle in irradiation of human tissue to check the human tissue parameter.